PRP Injection and the Buzz about PRP

What is PRP and why do you use it with Stem cell therapy?

PRP is a fraction of peripheral blood that stimulates healing. PRP can elicit a healing response by the use of platelets and numerous growth factors. Growth factors contained in Platelet-rich plasma are directly responsible for activating autologous adipose derived stem cells. Each growth factor plays important roles in our body’s wound healing and cell regeneration. Using PRP in effect acts as a double activation of your stem cells and is essential for proper distribution to areas in need of repair and rejuvenation. Research shows that the higher the amount of activated stem cells reintroduced back into your body the higher the likelihood of a positive response to stem cell therapy procedure.

 

How do you obtain the PRP?

We take a small amount of venous blood from you (the patient) and isolate the PRP layer. We take whole blood through sterile venipuncture for processing. Prior to the procedure the blood is transferred into a closed vacutainer tube and centrifuged to extract the PRP.

 

Why do you use PRP microneedling for facial rejuvenation?

Platelet Rich Plasma can help rejuvenate a patients facial appearance. Once processed PRP has been shown to contain 50% Red Blood Cells (RBC’s) and 50% stem cells (ASC’s). This may help with regeneration of facial collagen, thus reducing the appearance of fine lines and wrinkles.

What is the science behind PRP?

One use of PRP for stem cell activation is for the skin. Science knows unipotent stem cells lie dormant in the skin as they provide the building blocks for healing when one sustains a burn or cut. Until recently, physicians had no convenient way to stimulate those stem cells to grow new tissue. By utilizing the growth factors found in the blood (specifically the platelets), a physician can activate the unipotent stem cells already in the skin (and other areas) and tell those cells to grow new, younger-appearing skin (or other tissue where it is directed including musculoskeletal)

What 3 parts of the aging process can improve regarding the skin?

1. The skin color becomes a “younger” color because of new blood vessel formation.
2. New collagen formations in the dermis lift the face back to more youthful shape.
3. Because the growth factors are working to build a new dermis, the epidermis (the outer most layers of your skin) appears smoother.

Why do you use PRP microneedling for facial rejuvenation?

Platelet Rich Plasma can help rejuvenate a patients facial appearance. Once processed PRP has been shown to contain 50% Red Blood Cells (RBC’s) and 50% stem cells (ASC’s). This may help with regeneration of facial collagen, thus reducing the appearance of fine lines and wrinkles.

What is the Vampire Facelift®?

During the process of the Vampire Facelift® Procedure™, stem cell science is used to tell the body to grow new younger skin. There are Unipotent stem cells which grow only one specific tissue, and can be found in every part of the body. For example, unipotent stem cells in the pancreas grow new pancreatic tissues. Unipotent stem cells in the skin grow new skin. Thus, the FaceLift® Procedure™ takes the cosmetic rejuvenation process to a higher level!

Benefits include:
-Soften fine lines & wrinkles;
-Look refreshed & younger, with a more youthful skin texture, color & tone.

How is Platelet-rich plasma (PRP) similar to Hyaluronic Acid fillers?

PRP is similar to HA because it can also be injected to sculpt the face. But, here’s the best part: not only does the PRP cause an increase in the volume, PRP contains at least 8 growth factors.

What are the 8 Growth factors contained in PRP and how can they help me?

Functions and specific relation to the skin:

1. Epidermal Growth Factor (EGF) – Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.

2. Transforming Growth Factor- Promotes angiogenesis, up-regulates collagen production and inhibits degradation, promotes chemo attraction of inflammatory cells.

3. Vascular Endothelial Growth Factor (VEGF) – Endothelial cells promote angiogenesis during tissue hypoxia.

4. Fibroblast Growth Factor (FGF) – Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.

5. Platelet-Derived Growth Factor (PDGF) – Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.

6. Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.

7. Colony Stimulating Factors – Stimulates granulocyte and macrophage proliferation.

8. Keratinocyte Growth Factor – Fibroblasts stimulate keratinocyte migration, differentiation, and proliferation.

What is microneedling?

This is a nearly painless technique to inject PRP in the dermal layer of the skin to promote facial collagen. We apply a topical anesthetic well before the procedure begins to allow you the most procedural comfort as possible (Most patients sleep throughout the process). Post procedure we apply a state of the art cooling gel mask for our patients to wear home. For more information visit: www.dermapen.com

How exactly do you perform microneedling for facial rejuvenation?

We attach a one time use microneedle tip to a DermaPen that is studded with tiny fine “micro needles”. The microneedle gently pricks your skin stimulating the creation of new skin cells and regeneration of damaged cells. Your own PRP is then massaged into the treated skin. The goal is to stimulate the production of collagen and elastin, and the creation of new cells. Your skin will glow and immediately feel smoother and softer, with progressive improvements continuing for several months to rejuvenate.

Can you microneedle anywhere else?

Yes, we can also help rejuvenate the neck and décolletage.

 

Read more about:

Stem Cell Therapy Frequently Asked Questions

Stem Cell Therapy Procedure Highlights

Stem Cell Therapy and the FDA.